Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid

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Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid Basic information
Product Name:Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid
Synonyms:Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid;UTPγS;UTP-γ-S
CAS:79049-97-1
MF:C9H15N2O14P3S
MW:500.2
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Mol File:79049-97-1.mol
Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid Structure
Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid Chemical Properties
density 2.030±0.06 g/cm3(Predicted)
pka0.67±0.50(Predicted)
Safety Information
MSDS Information
Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid Usage And Synthesis
UsesUridine-5'-O-(3-thiotriphosphate) (UTPγS), a stable analogue of UTP, is a potent agonist of the P2Y2 and P2Y4 receptors with increased metabolic stability[1][2].
References[1] Anna-Karin Wihlborg, et al. Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction. Circ Res. 2006 Apr 14;98(7):970-6. DOI:10.1161/01.RES.0000217402.73402.cd
[2] Malin Malmsj, et al. The stable pyrimidines UDPβS and UTPγS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery. Br J Pharmacol. 2000 Sep;131(1):51-6. DOI:10.1038/sj.bjp.0703536
Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid Preparation Products And Raw materials
Preparation ProductsGDP
Tag:Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid(79049-97-1) Related Product Information
UTP - solution UTP - lyophilized S trisodium salt UTP, 100mM Sodium Solution RP-UTP-ALPHA-S SODIUM SALT UTP-γ-AmNS