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| Product Name: | GDP | | Synonyms: | [[5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxyphosphonic acid;5'-guanylate diphosphate (GDP);Guanosine-5'-diphosphate disodium salt (GDP);Guanosine 5''-diphosphoric acid;5'-GUANYLATE DIPHOSPHATE;5'-GDP;Guanosine 5'-pyrophosphate;Guo-5'-P2 | | CAS: | 146-91-8 | | MF: | C10H15N5O11P2 | | MW: | 443.2 | | EINECS: | 231-026-2 | | Product Categories: | | | Mol File: | 146-91-8.mol |  |
| density | 2.63±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | H2O: 50 mg/mL, clear, colorless | | pka | pK3:2.9;pK4:6.3;pk5:9.6 (25°C,μ=0.1) | | CAS DataBase Reference | 146-91-8(CAS DataBase Reference) |
| Uses | Guanosine 5''-Diphosphate is used in methods of modulating immune activity using modulators of STING and purinergic receptors and screening assays. | | Definition | ChEBI: GDP is a purine ribonucleoside 5'-diphosphate resulting from the formal condensation of the hydroxy group at the 5' position of guanosine with pyrophosphoric acid. It has a role as an Escherichia coli metabolite, a mouse metabolite and an uncoupling protein inhibitor. It is a guanosine 5'-phosphate and a purine ribonucleoside 5'-diphosphate. It is a conjugate acid of a GDP(2-). | | IC 50 | Human Endogenous Metabolite |
| | GDP Preparation Products And Raw materials |
| Raw materials | [(2R,3R,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-phosphoryl]oxy-phosphinic acid-->guanosine 5'-phosphoimidazolide-->Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid-->MANNOSE-->GTP-GAMMA-S SODIUM SALT-->UDP-->D-glucose-->5'-Guanylic acid | | Preparation Products | guanosine diphosphate 2-deoxy-2-fluoromannose ester-->[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate-->7-methylguanosine 5'-diphosphate(1+) |
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