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Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)-

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Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- Suppliers list
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Products Intro: Product Name:Bomedemstat
CAS:1990504-34-1
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Products Intro: Product Name:Bomedemstat
CAS:1990504-34-1
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Products Intro: Product Name:Bomedemstat
CAS:1990504-34-1
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CAS:1990504-34-1
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CAS:1990504-34-1
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Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- manufacturers

  • Bomedemstat
  • Bomedemstat pictures
  • $411.00
  • 2026-07-06
  • CAS:1990504-34-1
  • Purity: 98.07%
  • Supply Ability: 10g
Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- Basic information
Product Name:Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)-
Synonyms:Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)-;IMG-7289 (free base);N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)-Benzamide
CAS:1990504-34-1
MF:C28H34FN7O2
MW:519.61
EINECS:
Product Categories:
Mol File:1990504-34-1.mol
Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- Structure
Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- Chemical Properties
density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (192.45 mM; Need ultrasonic)
pka13.08±0.46(Predicted)
form Oil
color Colorless to light yellow
Safety Information
MSDS Information
Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- Usage And Synthesis
UsesBomedemstat is a styrenylcyclopropylamine LSD1 inhibitor, and an antitumor agent.
in vivo

Bomedemstat treatment (oral gavage; 45 mg/kg; once daily; 56 d) normalizes or improves blood cell counts, reduces spleen volumes, restores normal splenic architecture, and reduces bone marrow fibrosis[1].

Animal Model:Mx-Jak2V617F mice[1]
Dosage:45mg/kg
Administration:Oral gavage; 45mg/kg; once daily; 56 days
Result:Reduced splenomegaly significantly with a few treated mice normalizing their spleen weight, the 56-day course led to partial restoration of lymph follicles and spleen architecture by histological examination.
IC 50KDM1/LSD1
Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- Preparation Products And Raw materials
Tag:Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)-(1990504-34-1) Related Product Information
Benzamide, N-[(1S)-1-[(4-methyl-1-piperazinyl)carbonyl]-4-oxobutyl]-4-(1H-1,2,3-triazol-1-yl)- Bomedemstat dihydrochloride Benzamide, N-[(1S)-4-[[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]amino]-1-[(4-methyl-1-piperazinyl)carbonyl]butyl]-4-(1H-1,2,3-triazol-1-yl)- Bomedemstat Bomedemstat Impurity 6 1-Piperazinepentanoic acid, 4-methyl-δ-oxo-γ-[[4-(1H-1,2,3-triazol-1-yl)benzoyl]amino]-, (γS)-