NW-PROPYL-L-ARGININE HYDROCHLORIDE
| 中文名称 | NW-PROPYL-L-ARGININE HYDROCHLORIDE |
|---|---|
| 中文同义词 | (S)-2-氨基-5-(3-丙基胍基)戊酸盐酸盐;Nω-丙基-L-精氨酸盐酸盐 |
| 英文名称 | Nw-Propyl-L-arginine hydrochloride |
| 英文同义词 | Nw-Propyl-L-arginine hydrochloride;NωPropylLarginine hydrochloride,Nω Propyl L arginine hydrochloride;(S)-2-Amino-5-(3-propylguanidino)pentanoic acid hydrochloride;Nω-Propyl-L-arginine HCl |
| CAS号 | 2321366-46-3 |
| 分子式 | C9H21ClN4O2 |
| 分子量 | 252.74 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 2321366-46-3.mol |
| 结构式 |  |
NW-PROPYL-L-ARGININE HYDROCHLORIDE 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 油状物 |
| 颜色 | 无色至类白色 |
Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride 是一种高效、竞争性、高选择性的神经型一氧化氮合酶 (nNOS) 抑制剂，Ki为 57 nM。Nω-Propyl-L-arginine hydrochloride 对 nNOS 的选择性是内皮型一氧化氮合酶 (eNOS) 的 149 倍。
Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) hydrochloride (20 mg/kg; i.p.) blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity.
| Animal Model: | Male NMRI mice (30-40 g) (phencyclidine-induced stimulation) |
| Dosage: | 20 mg/kg |
| Administration: | I.p. |
| Result: | Markedly reduced the phencyclidineinduced disruption of prepulse inhibition and significantly reduced the phencyclidine-induced stimulation of locomotor activity. |
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/09/15 | HY-102062A | NW-PROPYL-L-ARGININE HYDROCHLORIDE Nω-Propyl-L-arginine hydrochloride | 2321366-46-3 | 5 mg | 940元 |
| 2026/09/15 | HY-102062A | NW-PROPYL-L-ARGININE HYDROCHLORIDE Nω-Propyl-L-arginine hydrochloride | 2321366-46-3 | 10 mM * 1 mL in DMSO | 1034元 |