| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Company Name: |
Accela ChemBio Inc. |
| Tel: |
+1-858-6993322 +86-18019713315 |
| Email: |
info@accelachem.com |
- Hydracarbazine
-
- $1520.00
-
2026-05-11
- CAS:3614-47-9
- Purity:
- Supply Ability: 10g
|
| | hydracarbazine Basic information |
| Product Name: | hydracarbazine | | Synonyms: | hydracarbazine;6-hydrazinopyridazine-3-carboxamide;6-hydrazinylpyridazine-3-carboxamide;6-Hydrazino-3-pyridazinecarboxamide;TH-2151;6-hydrazinylidene-1,6-dihydropyridazine-3-carboxamide;3-Pyridazinecarboxamide, 6-hydrazinyl-;Hidracarbazina | | CAS: | 3614-47-9 | | MF: | C5H7N5O | | MW: | 153.14 | | EINECS: | 2227887 | | Product Categories: | | | Mol File: | 3614-47-9.mol |  |
| | hydracarbazine Chemical Properties |
| Melting point | 249-250 °C (decomp) | | Boiling point | 361.8±25.0 °C(Predicted) | | density | 1.71±0.1 g/cm3(Predicted) | | pka | 12.21±0.20(Predicted) |
| | hydracarbazine Usage And Synthesis |
| Uses | Hydracarbazine is a pyridazine. Hydracarbazine can effectively lower blood pressure, it can be used for the research of high blood pressure[1][2]. | | Definition | ChEBI: Hydracarbazine is a heteroarene and an aromatic amide. | | in vivo | Hydracarbazine (1-4 mg/kg; i.v. once) induced in the dog, cat and rabbit hypotension by peripheral vasodilation, showed no inhibitory action on vasomotor centers and decreased the hypertensive effects of adrenaline, noradrenaline, 5-hydroxytryptamine, pituitrin, and splanchnic nerve stimulation[1].
Hydracarbazine (15-18 mg/kg; p.o. once daily) prevents the increased blood pressure and heart rate, reduces the renal histol and reduces the hypertensive syndrome with a combination of pempidine in high arterial pressure rats[2]. | | References | [1] Schmitt H, et al. Pharmacological study of a new hypotensor with a long duration of action: 1-hydrazino-4-carboxamidopyridazine (1325). Journal de Physiologie. 1992 52:525-36.
[2] Ghaye-Roquet J, et al. [Prevention of experimental hypertension in the rat by prolonged administration of a combination of antihypertensive agents]. Arch Int Pharmacodyn Ther. 1967 Mar;166(1):65-78. PMID:6034330 |
| | hydracarbazine Preparation Products And Raw materials |
|