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| | 5-chloro-7-bromo-8-quinolyl vinyl carbonate Basic information |
| | 5-chloro-7-bromo-8-quinolyl vinyl carbonate Chemical Properties |
| Melting point | 100.5°C | | density | 1.6514 (rough estimate) | | refractive index | 1.6110 (estimate) | | Water Solubility | 6mg/L(20 ºC) | | Henry's Law Constant | 2.4×102 mol/(m3Pa) at 25℃, MacBean (2012) | | EPA Substance Registry System | Halacrinate (34462-96-9) |
| | 5-chloro-7-bromo-8-quinolyl vinyl carbonate Usage And Synthesis |
| Definition | ChEBI: Halacrinate is a member of quinolines. | | Production Methods | Halacrinate is synthesised through a multi-step chemical process beginning with the construction of a quinoline ring, typically via a Skraup or Doebner–Miller reaction using aniline derivatives and carbonyl compounds. The quinoline core is then selectively halogenated to introduce chlorine at position 5 and bromine at position 7 through electrophilic aromatic substitution. Next, the 8-position is activated, often by hydroxylation, to enable esterification. The final step involves coupling the activated quinoline with acrylic acid or acryloyl chloride to form the prop-2-enoate ester, completing the Halacrinate molecule. | | Mechanism of action | Protective and curative. Quinoline fungicides work by inhibiting dihydroorotate dehydrogenase (DHODH), an enzyme crucial for pyrimidine biosynthesis in fungal cells. | | Pesticide Type | Fungicide |
| | 5-chloro-7-bromo-8-quinolyl vinyl carbonate Preparation Products And Raw materials |
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