2-Thiohydantoin

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2-Thiohydantoin Suppliers list
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel: 4006356688 18621169109
Email: market03@meryer.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 18930552037
Email: 3bsc@sina.com
Company Name: Alfa Aesar  
Tel: 400-6106006
Email: saleschina@alfa-asia.com
Company Name: Energy Chemical  
Tel: 400-0056266
Email: sales8178@energy-chemical.com
Company Name: Adamas Reagent, Ltd.  
Tel: 400-6009262 15618770481
Email: yhx@titansci.com

2-Thiohydantoin manufacturers
2-Thiohydantoin Basic information
Product Name:2-Thiohydantoin
Synonyms:2-Thioguidanthion;2-thio-hydantoi;2-thioxo-4-imidazolidinon;2-Thioxo-4-imidazolidinone;2-Thioxo-4-imidazolinone;4-Imidazolidinone,2-thioxo-;Glycine thiohydantoin;Hydantoin, 2-thio-
CAS:503-87-7
MF:C3H4N2OS
MW:116.14
EINECS:207-977-4
Product Categories:Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Ring Systems;Building Blocks;Heterocyclic Building Blocks;Imidazolines/Imidazolidines
Mol File:503-87-7.mol
2-Thiohydantoin Structure
2-Thiohydantoin Chemical Properties
Melting point 229-231 °C (dec.)(lit.)
density 1.346 (estimate)
vapor density 4 (vs air)
refractive index 1.6550 (estimate)
storage temp. Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka8.50±0.10(Predicted)
form Crystalline Powder
color White
InChI1S/C3H4N2OS/c6-2-1-4-3(7)5-2/h1H2,(H2,4,5,6,7)
InChIKeyUGWULZWUXSCWPX-UHFFFAOYSA-N
SMILESO=C1CNC(=S)N1
CAS DataBase Reference503-87-7(CAS DataBase Reference)
NIST Chemistry Reference4-Imidazolidinone, 2-thioxo-(503-87-7)
EPA Substance Registry System4-Imidazolidinone, 2-thioxo- (503-87-7)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-22
Safety Statements 36
WGK Germany 3
RTECS MU4200000
TSCA TSCA listed
HS Code 2934999090
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
2-Thiohydantoin Usage And Synthesis
Chemical PropertiesBROWN CRYSTALLINE POWDER
UsesReactant for synthesis of:• ;Drugs with antidiabetic activity1• ;Barbituric acid and thiohydantoin derivatives with antimicrobial activity2• ;Possible anticancer agents3• ;Fibroblast growth factor receptor 1 kinase inhibitors4• ;HIV-1 integrase inhibitors5Reactant for persilylation6
Uses2-Thiohydantoin is a useful synthetic intermediate. It is a reactant for synthesis of drugs with antidiabetic activity, barbituric acid and thiohydantoin derivatives with antimicrobial activity, and possible anticancer agents.
UsesReactant for synthesis of:
  • Drugs with antidiabetic activity
  • Barbituric acid and thiohydantoin derivatives with antimicrobial activity
  • Possible anticancer agents
  • Fibroblast growth factor receptor 1 kinase inhibitors
  • HIV-1 integrase inhibitors

Reactant for persilylation
2-Thiohydantoin Preparation Products And Raw materials
Preparation ProductsParabanic acid-->5-[(Z)-1,3-Benzodioxol-5-ylmethylidene]-2-thioxodihydro-1H-imidazol-4-one
Tag:2-Thiohydantoin(503-87-7) Related Product Information
Sodium thiosulfate BCDMH Iprodione Thioacetamide Phenytoin sodium Thioacetic acid 1,3-Dibromo-5,5-dimethylhydantoin 2-Thiobarbituric acid Dimethyloldimethyl hydantoin Hydantoin Pseudothiohydantoin Allantoin Phenylthiohydantoin-aspartic acid 1,3-Dimethyl-2-thiohydantoin PTH-serine 1-Acetyl-2-thiohydantoin Phenylthiohydantoin-tryptophan PTH-leucine