2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- manufacturers
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| | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- Basic information |
| Product Name: | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- | | Synonyms: | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]-;PI3K IN C96;PI3K inhibitor C 96;PI3K-IN-C96;PI-3K inhibitor C 96,PI3K inhibitor C 96 | | CAS: | 1502813-63-9 | | MF: | C11H8N2O3S | | MW: | 248.26 | | EINECS: | | | Product Categories: | | | Mol File: | 1502813-63-9.mol | ![2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- Structure](CAS/20210305/GIF/1502813-63-9.gif) |
| | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- Chemical Properties |
| density | 1.517±0.06 g/cm3(Predicted) | | pka | 6.96±0.20(Predicted) |
| | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- Usage And Synthesis |
| Description | PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase (PI3K). It displays potent activity against multiple myeloma in vitro and in vivo. | | Uses | PI3K-IN-7 (Compound C96) is a PI3K inhibitor. PI3K-IN-7 inhibits phosphorylation of AKT and the activation of an AKT downstream protein. PI3K-IN-7 induces apoptosis of the tumor cells. PI3K-IN-7 has low toxicity for normal cells. PI3K-IN-7 can be used for research of acute and chronic leukemia, multiple myeloma, lymphoma[1]. | | References | [1] Mao Xinliang, et al. PI3K small-molecule inhibitor and application thereof. CN103405437A. |
| | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2E)-3-(2-thienyl)-2-propen-1-ylidene]- Preparation Products And Raw materials |
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