5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

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5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Suppliers list
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5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite manufacturers
5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Basic information
Uses
Product Name:5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
Synonyms:DMT-dA(tac) amidite;5''-O-(4,4''-Dimethoxytrityl)-N6-Phenoxyacetyl-2''-deoxyadenosine-3''-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite;5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];DMT-dA(PAc) Phosphoramidite;5'-Dimethoxytrityl-N-phenoxyacetyl-2'-deoxyAdenosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite;5'-O-(4,4'-dimethoxytrityl)-N6-Phenoxyacetyl-2'-deoxyadenosine-3'-cyanoethyl Phosphoramidite
CAS:110543-74-3
MF:C48H54N7O8P
MW:887.96
EINECS:2017-001-1
Product Categories:DNA Amidites;Fast Deprotection DNA Amidites;Sigma-Proligo;Pharmaceutical
Mol File:110543-74-3.mol
5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Structure
5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Chemical Properties
storage temp. Store at -20°C
solubility DMSO: Soluble: = 10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml
form Solid
pka7.87±0.43(Predicted)
color White to off-white
Safety Information
MSDS Information
5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Usage And Synthesis
Uses2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a useful research chemical compound.
UsesDMT-dA(PAc) Phosphoramidite is a dIPhosphoramidite and can be used for DNA or RNA synthesis.
References[1] Keyhani S, et al. Chemo-Enzymatic Synthesis of Position-Specifically Modified RNA for Biophysical Studies including Light Control and NMR Spectroscopy. Angew Chem Int Ed Engl. 2018 Sep 10;57(37):12017-12021. DOI:10.1002/anie.201807125
[2] XIE Z, YANG Y, WANG Z, et al. Dithioethanol (DTE)-Conjugated Deoxyribose Cyclic Dinucleotide Prodrugs (DTE-dCDNs) as STING Agonist[J]. International Journal of Molecular Sciences, 2023, 53 17. DOI: 10.3390/ijms25010086
5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Preparation Products And Raw materials
Tag:5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(110543-74-3) Related Product Information
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyadenosine DMT-2'O-TBDMS-RA(TAC) AMIDITE 0.5G AB Phenoxyacetamide Dimethyl N,N-diisopropylphosphoramidite Diethyl N,N-diisopropylphosphoramidite 2'-Deoxynebularine CEP PHEAC-DMT-DEOXYADENOSINE Dimethyl N,N-Diethyl Phosphoramidite 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-(Dimethoxytrityl)-2'-deoxynebularine (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite N6-Pheac-deoxyadenosine 5'-O-(4,4'-Dimethoxytrityl)-N6-methyl-2'-deoxyadenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite 5'-O-(Dimethoxytrityl)-N6-methyl-2'-deoxyadenosine Dspacer CEP 3-(4,4'-Dimethoxytrityl)propandiol-1-N,N-diisopropyl (beta-cyanoethyl) phosphoramidite 6-(beta-Hydroxyethylamino)-purine