1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]-

Request For Quotation
1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]- Suppliers list
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Shaanxi Kebele Pharmaceutical R&D Co., Ltd  
Tel: 13119135307
Email: 3866620171@qq.com
Company Name: Henan Yinuokai New Materials Co., Ltd.  
Tel: 15670530983
Email: 3872928368@qq.com
Company Name: ATK CHEMICAL COMPANY LIMITED  
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]- Basic information
Product Name:1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]-
Synonyms:1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]-;ARN22089
CAS:2248691-29-2
MF:C23H27N5
MW:373.49
EINECS:
Product Categories:
Mol File:2248691-29-2.mol
1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]- Structure
1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]- Chemical Properties
Boiling point 576.6±50.0 °C(Predicted)
density 1.158±0.06 g/cm3(Predicted)
pka9.51±0.10(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]- Usage And Synthesis
UsesARN22089 is a oral active novel class of trisubstituted pyrimidine, blocks the interaction of CDC42 GTPases with specific downstream effectors. ARN22089 blocks tumor growth in BRAF mutant mouse melanoma model[1].
References[1] Brindani N, et al. Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer. J Med Chem. 2023;66(8):5981-6001. DOI:10.1021/acs.jmedchem.3c00276
1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]- Preparation Products And Raw materials
Tag:1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]-(2248691-29-2) Related Product Information
1,3-Benzenediamine, N1,N1-dimethyl-N3-[6-phenyl-2-(4-piperidinyl)-4-pyrimidinyl]- 2-Cyclopropyl-4-phenyl-6-piperazin-1-yl-pyrimidine 1-(2-Cyclopropyl-6-phenyl-pyrimidin-4-yl)-pyrrolidin-3-ylamine Anti-cancer compound library Immunology/Inflammation Compound Library Kinase Inhibitor Library