1-formylisoquinoline thiosemicarbazone

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Company Name: Shaanxi Dideu Medichem Co. Ltd  
Tel: 81148925 17391631969
Email: 1023@dideu.com
Company Name: Shaanxi Dideu New Materials Co. Ltd  
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1-formylisoquinoline thiosemicarbazone Basic information
Product Name:1-formylisoquinoline thiosemicarbazone
Synonyms:1-formylisoquinoline thiosemicarbazone;1-Isoquinolinecarbaldehyde thiosemicarbazone;IQ-1;Hydrazinecarbothioamide, 2-(1-isoquinolinylmethylene)-
CAS:2365-26-6
MF:C11H10N4S
MW:230.29
EINECS:
Product Categories:
Mol File:2365-26-6.mol
1-formylisoquinoline thiosemicarbazone Structure
1-formylisoquinoline thiosemicarbazone Chemical Properties
density 1.2608 (rough estimate)
refractive index 1.5500 (estimate)
Safety Information
ToxicityLD50 intraperitoneal in mouse: 800mg/kg
MSDS Information
1-formylisoquinoline thiosemicarbazone Usage And Synthesis
UsesIQ 1 disrupts Wnt signaling. IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription.
1-formylisoquinoline thiosemicarbazone Preparation Products And Raw materials
Tag:1-formylisoquinoline thiosemicarbazone(2365-26-6) Related Product Information
1-formylisoquinoline thiosemicarbazone 2-Formylpyridine thiosemicarbazone