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| | butyl-delta(9)-tetrahydrocannabinol Basic information |
| Product Name: | butyl-delta(9)-tetrahydrocannabinol | | Synonyms: | butyl-delta(9)-tetrahydrocannabinol;(6aR,10aR)-3-butyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol;6H-Dibenzo[b,d]pyran-1-ol, 3-butyl-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-, (6aR-trans)-;Δ9-THCB;Δ9-THCB (CRM);Delta9-Tetrahydrocannabibutol (Delta9-THCB) solution | | CAS: | 60008-00-6 | | MF: | C20H28O2 | | MW: | 300.44 | | EINECS: | | | Product Categories: | | | Mol File: | 60008-00-6.mol |  |
| | butyl-delta(9)-tetrahydrocannabinol Chemical Properties |
| Boiling point | 375.7±42.0 °C(Predicted) | | density | 1.024±0.06 g/cm3(Predicted) | | storage temp. | -10 to -25°C | | solubility | DMF: 50 mg/ml
DMF: PBS (pH 7.2) (1:3): 0.25 mg/ml
DMSO: 60 mg/ml
Ethanol: 35 mg/ml
Methanol: 30 mg/ml | | pka | 9.78±0.60(Predicted) |
| WGK Germany | WGK 2 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1 |
| | butyl-delta(9)-tetrahydrocannabinol Usage And Synthesis |
| Uses | Δ9-THCB (Δ9-Tetrahydrocannabutol) has a high affinity for human CB1 and CB2 receptors with the Ki values of 15 nM and 51 nM, respectively. Δ9-THCB (Δ9-Tetrahydrocannabutol) has analgesic and anti-inflammatory activities and plays partial agonistic effects on CB1 receptor in mice[1]. | | IC 50 | CB1: 15 nM (Ki); CB2: 51 nM (Ki) | | References | [1] Linciano P, et al. Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol. J Nat Prod. 2020 Jan 24;83(1):88-98. DOI:10.1021/acs.jnatprod.9b00876
[2] SMITH R. IDENTIFICATION OF BUTYL CANNABINOIDS IN MARIJUANA[J]. Journal of forensic sciences, 1997, 21 1: 610-618. DOI: 10.1520/jfs14173j
[3] HARVEY D I. Characterization of the butyl homologues of Δ1-tetrahydrocannabinol, cannabinol and cannabidiol in samples of cannabis by combined gas chromatography and mass spectrometry[J]. Journal of Pharmacy and Pharmacology, 1976, 28 4: 280-285. DOI: 10.1111/j.2042-7158.1976.tb04153.x |
| | butyl-delta(9)-tetrahydrocannabinol Preparation Products And Raw materials |
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