N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide

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N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide manufacturers

  • Kras4B G12D-IN-1
  • Kras4B G12D-IN-1 pictures
  • $93.00
  • 2026-07-27
  • CAS:2042365-85-3
  • Purity: 99.90%
  • Supply Ability: 10g
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide Basic information
Product Name:N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide
Synonyms:N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide;Kras4B G12D-IN-1;Kras4B G12D-IN-1, 10 mM in DMSO
CAS:2042365-85-3
MF:C16H21ClN2O4S
MW:372.87
EINECS:
Product Categories:
Mol File:2042365-85-3.mol
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide Structure
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide Chemical Properties
Boiling point 558.0±60.0 °C(Predicted)
density 1.287±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka10.42±0.40(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide Usage And Synthesis
UsesKras4B G12D-IN-1 is a Kras4B G12D inhibitor with anticancer effects. Kras4B G12D-IN-1 decreases Kras protein expression in mouse embryonic fibroblasts (MEF) expressing Kras4B G12D (WO2016179558A1, Comp 994566)[1].
IC 50KRas G12D
References[1] Frank Mccormick, et al. K-ras modulators. WO2016179558A .
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide Preparation Products And Raw materials
Tag:N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide(2042365-85-3) Related Product Information
N-[[(3S)-1-(5-Chloro-2-methoxybenzoyl)-3-piperidinyl]methyl]ethenesulfonamide 2-Propen-1-one, 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]- 2,7-Diazaspiro[4.4]nonane-2-acetamide, α-cyclopentyl-7-[[(2R,3R)-3-cyclopropyl-1-methyl-2-aziridinyl]carbonyl]-N-[(1R,10S,12S,18S)-1-[5-(4-cyclopropyl-1-piperazinyl)-2-[(1S)-1-methoxyethyl]-3-pyridinyl]-2,7,8,10,11,12,13,16,17,18,19,21,22,23-tetradecahydro-22,22-dimethyl-13,19-dioxo-2-(2,2,2-trifluoroethyl)-15H-3,5-etheno-14,18-imino-6,10-methano-6H-pyrrolo[3,4-g][1,12,4,18]dioxadiazacyclodocosin-12-yl]-, (αS,5S)- NAV2729 RMC6291 RMC-7977