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(2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate Suppliers list
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Ferroptocide
CAS:2505218-38-0
Purity:95% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Ferroptocide
CAS:2505218-38-0
Package:10mg/RMB 4140;1mg/RMB 525;5mg/RMB 2340
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| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:Ferroptocide
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| Company Name: |
Neobioscience Co., Ltd.
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| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:Ferroptocide
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| | (2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate Basic information |
| Product Name: | (2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate | | Synonyms: | (2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate;Ferroptocide | | CAS: | 2505218-38-0 | | MF: | C30H36ClN3O7 | | MW: | 586.08 | | EINECS: | | | Product Categories: | | | Mol File: | 2505218-38-0.mol | ![(2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate Structure](CAS/20210305/GIF/2505218-38-0.gif) |
| | (2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate Chemical Properties |
| Boiling point | 695.2±65.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 11.97±0.70(Predicted) |
| | (2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate Usage And Synthesis |
| Uses | Ferroptocide is a cell death inducer that triggers ferroptosis and has anti-tumor activity. Ferroptocide can induce oxidative stress, leading to G2/M cell cycle arrest and apoptosis activation in LNCaP cells, while also effectively inhibiting the cell viability of both LNCaP and TRAMP-C1 cells. Ferroptocide can be used to study its capability to induce mitochondrial autophagy and to trigger immunogenic cell death (ICD) in prostate cancer cells[1]. | | References | [1] Hillary Shah, et al. Evaluation of Ferroptocide (FTC) As a Potential Immunogenic Cell Death Inducing Agent in Prostate Cancer Cells. Biochemistry and Molecular Biology. 2021.35.S1.03356. |
| | (2S,3aS,4S,5R,7R,8S,8aS,9R)-Octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,2,4]triazolo[1,2-a]pyridazin-6-yl)-1H-3a,8-propanoazulen-7-yl 2-chloroacetate Preparation Products And Raw materials |
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