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| | 4-Hydroxyphenylpyruvic acid Basic information |
| Product Name: | 4-Hydroxyphenylpyruvic acid | | Synonyms: | Pyruvic acid, (p-hydroxyphenyl)-;Testacid;4-HYDROXYPHENYLPYRUVIC ACID 99%;4-Hydrixyphenyruvic acid;4-hydroxy-a-oxo-benzenepropanoic acid;3-(4-Hydroxyphenyl)pyruvate;2-Oxo-3-(4-hydroxyphenyl)propionic acid;α-Oxo-4-hydroxybenzenepropionic acid | | CAS: | 156-39-8 | | MF: | C9H8O4 | | MW: | 180.16 | | EINECS: | 205-852-9 | | Product Categories: | Miscellaneous;API intermediates | | Mol File: | 156-39-8.mol |  |
| | 4-Hydroxyphenylpyruvic acid Chemical Properties |
| Melting point | 219-220 °C (dec.) (lit.) | | Boiling point | 272.96°C (rough estimate) | | density | 1.2933 (rough estimate) | | refractive index | 1.4500 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | ethanol: soluble50mg/mL | | form | crystalline | | pka | 2.50±0.54(Predicted) | | color | off-white to tan | | Water Solubility | slightly soluble | | BRN | 2691632 | | Stability: | Hygroscopic | | InChI | 1S/C9H8O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,10H,5H2,(H,12,13) | | InChIKey | KKADPXVIOXHVKN-UHFFFAOYSA-N | | SMILES | OC(=O)C(=O)Cc1ccc(O)cc1 | | CAS DataBase Reference | 156-39-8(CAS DataBase Reference) | | NIST Chemistry Reference | Benzenepropanoic acid, 4-hydroxy-«alpha»-oxo-(156-39-8) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | RTECS | UZ1000000 | | HS Code | 29189900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2 |
| | 4-Hydroxyphenylpyruvic acid Usage And Synthesis |
| Chemical Properties | grey to orange-brown powder | | Uses | 4-Hydroxyphenylpyruvic Acid is general organic reagent used in the synthesis of latifolicinin A analogs as inhibitors of breast cancer. Also used in the preparation of amperometric biosensors for β-triketone herbicides based on hydroxyphenylpyruvate. | | Definition | ChEBI: An oxo carboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. | | General Description | 4-hydroxyphenylpyruvic acid can be determined in pork meat and Iberian ham samples by a sensitive method of multiple reaction monitoring (MRM) by mass spectrometry. | | Purification Methods | p-Hydroxyphenylpyruvic acid [156-39-8] M 180.2, m 220o(dec), pKEst ~2.3. Crystallise it three times from 0.1M HCl/EtOH (4:1, v/v) immediately before use [Rose & Powell Biochem J 87 541 1963], or from Et2O. The 3,4-dinitrophenylhydrazone has m 178o. [Beilstein 10 IV 3630.] |
| | 4-Hydroxyphenylpyruvic acid Preparation Products And Raw materials |
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