替莫贝松
| 中文名称 | 替莫贝松 |
|---|---|
| 中文同义词 | 替莫贝松;化合物 T13927;化合物:Timobesone CAS:87116-72-1;化合物：Timobesone CAS:87116-72-1 |
| 英文名称 | Timobesone |
| 英文同义词 | 9-Fluoro-11β,17α-dihydroxy-16β-methyl-3-oxoandrosta-1,4-diene-17-carbothioic acid S-methyl ester;Timobesone [inn];Timobesone;Androsta-1,4-diene-17-carbothioic acid, 9-fluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-methyl ester, (11β,16β,17α)- |
| CAS号 | 87116-72-1 |
| 分子式 | C22H29FO4S |
| 分子量 | 408.531 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 87116-72-1.mol |
| 结构式 |  |
替莫贝松 性质
| 沸点 | 553.0±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.30±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 12.13±0.70(Predicted) |
Timobesone是一种局部皮质类固醇，但从未上市。
The increase in the solubility of Timobesone acetate in the micellar solutions is dependent on the type and concentration of surfactant. The solubilizing capacity of the surfactant micelles and the distribution coefficient of Timobesone acetate in aqueous micellar solutions are found to increase with increasing length of the hydrophobic fatty acid group.