2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)-

Company Name:	Shanghai Beckham Medical Technology Co., Ltd
Tel:	13816613772
Email:	huahero21@sina.com

2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)- Basic information

Product Name:	2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)-
Synonyms:	2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)-;(E)-N-(4-(1-(3-Aminobenzoyl)piperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide;Nampt-IN-15
CAS:	2222981-61-3
MF:	C24H30N4O2
MW:	406.52
EINECS:
Product Categories:
Mol File:	2222981-61-3.mol

2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)- Chemical Properties

Boiling point	691.0±55.0 °C(predicted)
density	1.166±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
form	Solid
pka	14.12±0.46(predicted)

Safety Information

MSDS Information

2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)- Usage And Synthesis

Uses	Nampt-IN-15 (Example 3) is an Nampt inhibitor. Nampt-IN-15 shows cytotoxicity against BxPC-3, HepG2, L540cy and MOLM-13, with IC50s of 38.5 nM, 8 nM, 8.5 nM, 7 nM respectively[1].
References	[1] Christopher Scott NEUMANN, et al. Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors. Patent. WO2018075600

2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)- Preparation Products And Raw materials

Tag:2-Propenamide, N-[4-[1-(3-aminobenzoyl)-4-piperidinyl]butyl]-3-(3-pyridinyl)-, (2E)-(2222981-61-3) Related Product Information

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