Sigma-2 Radioligand 1

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Sigma-2 Radioligand 1 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Sigma-2 Radioligand 1 Basic information
Product Name:Sigma-2 Radioligand 1
Synonyms:Sigma-2 Radioligand 1;2H-Benzimidazol-2-one, 1-[4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)butyl]-3-(2-fluoroethyl)-1,3-dihydro-
CAS:2860554-32-9
MF:C24H30FN3O3
MW:427.51
EINECS:
Product Categories:
Mol File:2860554-32-9.mol
Sigma-2 Radioligand 1 Structure
Sigma-2 Radioligand 1 Chemical Properties
Boiling point 560.156±50.00 °C(Press: 760.00 Torr)(predicted)
density 1.181±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka8.069±0.20(predicted)
Safety Information
MSDS Information
Sigma-2 Radioligand 1 Usage And Synthesis
UsesSigma-2 Radioligand 1 (compound 1) is a Sigma-2 selective ligand. Sigma-2 Radioligand 1 has good biodistribution in mice and good in vivo activity in rats. [18F] Modified Sigma-2 Radioligand 1 for visualization of tumors in micro-PET/CT imaging, exhibiting high tumor uptake and tumor-to-background ratio. Experiments show that Sigma-2 Radioligand 1 binds highly specifically in U87MG glioma xenografts[1].
References[1] Wang T, et al. Development of a Highly Specific 18F-Labeled Radioligand for Imaging of the Sigma-2 Receptor in Brain Tumors. J Med Chem. 2023 Sep 13.. . DOI:10.1021/acs.jmedchem.3c00735
Sigma-2 Radioligand 1 Preparation Products And Raw materials
Tag:Sigma-2 Radioligand 1(2860554-32-9) Related Product Information
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