1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-

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1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Shanghai meikai technology co., ltd  
Tel: 021-68689288 15300790979
Email: info@mkbio.com.cn
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Basic information
Product Name:1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-
Synonyms:1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-;(7S)-BAY-593;1-Propanone,3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-
CAS:2413068-25-2
MF:C26H31F3N2O3
MW:476.53
EINECS:
Product Categories:
Mol File:2413068-25-2.mol
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Structure
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Chemical Properties
Boiling point 575.1±50.0 °C(predicted)
density 1.25±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka10.49±0.40(predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Usage And Synthesis
Uses(7S)-BAY-593 is the S-enantiomer of BAY-593 (HY-161573). BAY-593 is an orally active GGTase-I inhibitor. BAY-593 can block YAP1/TAZ signaling in animals and has antitumor activity[1].
IC 50YAP/TAZ-TEAD; GGTase I
References[1] Graham K, et al. Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol. 2024 Mar 19:S2451-9456(24)00087-4. DOI:10.1016/j.chembiol.2024.02.013
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Preparation Products And Raw materials
Tag:1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-(2413068-25-2) Related Product Information
tert-butyl (R)-1-(2-methoxyphenyl)-9-((R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl)-3,9-diazaspiro[5.5]undecane-3-carboxylate 1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- BAY-593 Anti-Aging Compound Library Anti-cancer compound library Stem Cell Signaling Compound Library