| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
|
| | c-Fms-IN-15 Basic information |
| Product Name: | c-Fms-IN-15 | | Synonyms: | c-Fms-IN-15;1,5-Naphthyridine-4-carboxamide, N-methyl-2-[4-[[[[4-(4-methyl-1-piperazinyl)-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]- | | CAS: | 3047930-25-3 | | MF: | C29H28F3N7O2 | | MW: | 563.57 | | EINECS: | | | Product Categories: | | | Mol File: | 3047930-25-3.mol |  |
| | c-Fms-IN-15 Chemical Properties |
| Boiling point | 661.4±55.0 °C(predicted) | | density | 1.364±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 12.72±0.46(predicted) |
| | c-Fms-IN-15 Usage And Synthesis |
| Uses | c-Fms-IN-15 (compound 8g) is a potent inhibitor of FMS kinase, with the IC50 of 563 nM[1]. | | References | [1] Anusha Sebastian, et al. Design, synthesis, biological evaluation, and in silico studies of novel pyridopyridine derivatives as anticancer candidates targeting FMS kinase. Eur J Med Chem. 2024 Aug 5:274:116557. DOI:10.1016/j.ejmech.2024.116557 |
| | c-Fms-IN-15 Preparation Products And Raw materials |
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