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| | Isotonitazene (citrate) Basic information |
| | Isotonitazene (citrate) Chemical Properties |
| | Isotonitazene (citrate) Usage And Synthesis |
| Description | Isotonitazene (citrate) (Item No. 40425) is an analytical reference standard categorized as an opioid.1,2,3 Isotonitazene has analgesic effects in mice.4 It has been associated with overdoses.5 Isotonitazene is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use. | | References | [1] A. F. CASY J. W. Ionisation constants and partition coefficients of some analgesically active 2-benzylbenzimidazole derivatives and related compounds[J]. Journal of Pharmacy and Pharmacology, 1966, 18 10: 677-683. DOI: 10.1111/j.2042-7158.1966.tb07782.x
[2] PETER BLANCKAERT. Report on a novel emerging class of highly potent benzimidazole NPS opioids: Chemical and in vitro functional characterization of isotonitazene[J]. Drug Testing and Analysis, 2019, 12 4: 422-430. DOI: 10.1002/dta.2738
[3] MARTHE M. VANDEPUTTE. Synthesis, Chemical Characterization, and μ-Opioid Receptor Activity Assessment of the Emerging Group of “Nitazene” 2-Benzylbenzimidazole Synthetic Opioids.[J]. ACS Chemical Neuroscience, 2021. DOI: 10.22541/au.160520665.59016513/v2
[4] ISTVÁN UJVÁRY*. DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles[J]. ACS Chemical Neuroscience, 2021, 12 7: 1072-1092. DOI: 10.1021/acschemneuro.1c00037
[5] CHELSEA L SHOVER. Emerging Characteristics of Isotonitazene-Involved Overdose Deaths: A Case-Control Study.[J]. Journal of Addiction Medicine, 2021, 15 5: 429-431. DOI: 10.1097/adm.0000000000000775
[6] LAURA B KOZELL. Pharmacologic Characterization of Substituted Nitazenes at μ, κ, and Δ Opioid Receptors Suggests High Potential for Toxicity.[J]. Journal of Pharmacology and Experimental Therapeutics, 2024: 219-228. DOI: 10.1124/jpet.123.002052 |
| | Isotonitazene (citrate) Preparation Products And Raw materials |
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