Boc-D-Val-OMe manufacturers
- Boc-D-Val-Ome
-
-
2026-09-11
- CAS:106391-85-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T
|
| | Boc-D-Val-OMe Basic information |
| Product Name: | Boc-D-Val-OMe | | Synonyms: | BOC-D-VALINE METHYL ESTER;N-BOC-D-VALINE METHYL ESTER;N-tert-Butoxycarbonyl-D-valine methyl ester;D-Boc valine methyl ester;methyl (2R)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate;methyl (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanoate;D-Valine,N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester;Boc-D-Val-OMe | | CAS: | 106391-85-9 | | MF: | C11H21NO4 | | MW: | 231.29 | | EINECS: | | | Product Categories: | | | Mol File: | 106391-85-9.mol |  |
| | Boc-D-Val-OMe Chemical Properties |
| Boiling point | 306.0±25.0 °C(Predicted) | | density | 1.020±0.06 g/cm3(Predicted) | | storage temp. | Store at Room Tem. | | pka | 11.13±0.46(Predicted) |
| | Boc-D-Val-OMe Usage And Synthesis |
| Uses | D-Boc Valine methyl ester is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1]. | | References | [1] Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45. PMID:12702571 |
| | Boc-D-Val-OMe Preparation Products And Raw materials |
|