Ac-IETD-AMC (trifluoroacetate salt)

Request For Quotation
Ac-IETD-AMC (trifluoroacetate salt) Suppliers list
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
Ac-IETD-AMC (trifluoroacetate salt) Basic information
Product Name:Ac-IETD-AMC (trifluoroacetate salt)
Synonyms:Ac-IETD-AMC (trifluoroacetate salt)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
Ac-IETD-AMC (trifluoroacetate salt) Structure
Ac-IETD-AMC (trifluoroacetate salt) Chemical Properties
solubility DMSO: Soluble: =10 mg/mL
Safety Information
MSDS Information
Ac-IETD-AMC (trifluoroacetate salt) Usage And Synthesis
DescriptionAc-IETD-AMC is a fluorogenic substrate for caspase-8.1 Upon enzymatic cleavage by caspase-8, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-8 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.WARNING This product is not for human or veterinary use.
References[1] V FROST  A J S  S Al Mehairi. Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27KIP1 in transformed lymphoid cells[J]. Oncogene, 2001, 20 22: 2737-2748. DOI: 10.1038/sj.onc.1204367
Ac-IETD-AMC (trifluoroacetate salt) Preparation Products And Raw materials
Tag:Ac-IETD-AMC (trifluoroacetate salt) Related Product Information
Ac-DMQD-AMC (trifluoroacetate salt) Ac-WEAD-AMC (trifluoroacetate salt) Ac-VEID-AMC (ammonium acetate salt) Ac-IETD-AFC (trifluoroacetate salt) Ac-Leu-Glu-His-Asp-AMC