| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
1-Ethyl-4-(4-nitrophenyl)piperazine manufacturers
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| | 1-Ethyl-4-(4-nitrophenyl)piperazine Basic information |
| | 1-Ethyl-4-(4-nitrophenyl)piperazine Chemical Properties |
| Boiling point | 381.9±37.0 °C(Predicted) | | density | 1.163±0.06 g/cm3(Predicted) | | pka | 7.76±0.10(Predicted) | | form | Solid |
| | 1-Ethyl-4-(4-nitrophenyl)piperazine Usage And Synthesis |
| Synthesis | GENERAL METHOD: 4-Fluoronitrobenzene (2 g, 14.2 mmol) and anhydrous K2CO3 (2.2 g, 15.6 mmol) were dissolved in DMSO (5 mL) and stirred at room temperature for 10 minutes. N-ethylpiperazine (14.2 mmol) was slowly added dropwise and the reaction mixture continued to be stirred at room temperature for 10 hours. After completion of the reaction, the mixture was poured into ice water and precipitated, the precipitate was collected by filtration and dried to give 1-ethyl-4-(4-nitrophenyl)piperazine. | | References | [1] Bulletin of the Korean Chemical Society, 2015, vol. 36, # 7, p. 1863 - 1873
[2] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 5, p. 1092 - 1099
[3] Patent: US2004/122237, 2004, A1. Location in patent: Page 180
[4] Archives of Pharmacal Research, 2016, vol. 39, # 5, p. 603 - 617
[5] European Journal of Medicinal Chemistry, 2019, p. 690 - 709 |
| | 1-Ethyl-4-(4-nitrophenyl)piperazine Preparation Products And Raw materials |
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