- Inecalcitol
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- $998.00
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2021-05-12
- CAS:163217-09-2
- Min. Order: 1mg
- Purity: 95%
- Supply Ability: 10g
- INECALCITOL
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- $7.00
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2020-02-14
- CAS: 163217-09-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| | INECALCITOL Basic information |
| Product Name: | INECALCITOL | | Synonyms: | INECALCITOL;1,3-Cyclohexanediol,5-[(2E)-2-[(1R,3aR,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-diMethyl-3-hexyn-1-yl]-7a-Methyl-4H-inden-4-ylidene]ethylidene]-,(1R,3R)-;(1R,3R)-5-[(2E)-2-[(1R,3aR,7aR)-1-[(2R)-6-hydroxy-6-methylhept-4-yn-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol;(7E)-19-Nor-9,10-seco-14b-cholesta-5,7-dien-23-yne-1a,3b,25-triol;anticancer,antiproliferative,Vitamin D,ETV1,Pim-1,Vitamin D receptor,Apoptosis,VDR,VD/VDR,Inecalcitol,Inhibitor,inhibit;19-Nor-9,10-secocholesta-5,7-dien-23-yne-1,3,25-triol, (1α,3β,7E,14β)-;Inecalcitol, 10 mM in DMSO;Enocalciferol | | CAS: | 163217-09-2 | | MF: | C26H40O3 | | MW: | 400.59 | | EINECS: | | | Product Categories: | | | Mol File: | 163217-09-2.mol |  |
| | INECALCITOL Chemical Properties |
| Boiling point | 568.6±50.0 °C(Predicted) | | density | 1.163 | | storage temp. | 4°C, protect from light, stored under nitrogen | | solubility | DMSO: Soluble | | form | Solid | | pka | 13.12±0.29(Predicted) | | color | Off-white to light yellow |
| | INECALCITOL Usage And Synthesis |
| Uses | Inecalcitol is a derivative of Vitamin D (V676045), the vitamin that mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. It occurs in and is isolated from fish liver oils. | | References | [1] GUY EELEN. Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.[J]. Molecular Pharmacology, 2005, 67 5: 1566-1573. DOI: 10.1124/mol.104.008730
[2] L VERLINDEN. Two novel 14-Epi-analogues of 1,25-dihydroxyvitamin D3 inhibit the growth of human breast cancer cells in vitro and in vivo.[J]. Cancer research, 2000, 60 10: 2673-2679.
[3] PETRA DE HAES . 1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage[J]. Journal of photochemistry and photobiology. B, Biology, 2005, 78 2: Pages 141-148. DOI: 10.1016/j.jphotobiol.2004.09.010
[4] MICHAEL S K WONG. Vitamin D derivatives acutely reduce endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat.[J]. American journal of physiology. Heart and circulatory physiology, 2008, 295 1: H289-96. DOI: 10.1152/ajpheart.00116.2008 |
| | INECALCITOL Preparation Products And Raw materials |
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