2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

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2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide manufacturers
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Basic information
Product Name:2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide
Synonyms:2-(2-aminopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide;InterMediate B of Raltegravir;2-(2-AMinopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-ethyl-6-oxo-1,6-dihydropyriMidine-4-carboxaMide;2-(1-amino-1-methyl-ethyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid 4-fluoro-benzylamide;Raltegravir USP Impurity A;RLT-8;2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1;6-dihydropyrimidine-4-carboxamide
CAS:518048-03-8
MF:C16H19FN4O3
MW:334.35
EINECS:1592732-453-0
Product Categories:Fluorine series;intermediate;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds;Amines
Mol File:518048-03-8.mol
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Structure
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Chemical Properties
Melting point 105-107°C
density 1.35
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Very Slightly, Heated), Pyridine (Slightly)
pka4.50±1.00(Predicted)
form Solid
color White to Off-White
Safety Information
HS Code 2933599590
MSDS Information
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Usage And Synthesis
Chemical PropertiesWhite Solid (Powder)
UsesAn labelled intermediate in the preparation of labelled HIV-integrase inhibitors
UsesAn intermediate in the preparation of HIV-integrase inhibitors
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Preparation Products And Raw materials
Preparation ProductsRaltegravir
Tag:2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide(518048-03-8) Related Product Information
Raltegravir USP RC E Raltegravir EP impurity H Raltegravir Oxalamide Impurity Raltegravir EP impurity D Raltegravir Diketo Methoxy Impurity Raltegravir EP impurity C Raltegravir potassium Raltegravir Diketo Ethoxy Impurity Raltegravir USP Impurity C Raltegravir -D-Glucuronide Raltegravir 2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Benzyl [1-[4-[[(4-fluorobenzyl)amino]carbonyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]-1-methylethyl]carbamate