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| | N,N-Dimethyl-4-(5-methyl-1H-benzo[d]imidazol-2-yl)benzenamine Basic information |
| Product Name: | N,N-Dimethyl-4-(5-methyl-1H-benzo[d]imidazol-2-yl)benzenamine | | Synonyms: | 2-[4(-DiMethylaMino)phenyl]-5-MethylbenziMidazole, 95%;Dimethyl-[4-(5-methyl-1H-benzoimidazol-2-yl)-phenyl]-amine;Benzenamine, N,N-dimethyl-4-(6-methyl-1H-benzimidazol-2-yl)-;N,N-dimethyl-4-(6-methyl-1H-benzo[d]imidazol-2-yl)aniline;N,N-Dimethyl-4-(5-methyl-1H-benzimidazol-2-yl)-benzenamine;V-161;N,N-Dimethyl-4-(5-methyl-1H-benzo[d]imidazol-2-yl)benzenamine | | CAS: | 69570-95-2 | | MF: | C16H17N3 | | MW: | 251.33 | | EINECS: | | | Product Categories: | | | Mol File: | 69570-95-2.mol | ![N,N-Dimethyl-4-(5-methyl-1H-benzo[d]imidazol-2-yl)benzenamine Structure](CAS/GIF/69570-95-2.gif) |
| | N,N-Dimethyl-4-(5-methyl-1H-benzo[d]imidazol-2-yl)benzenamine Chemical Properties |
| Melting point | 209.5-211.0 °C | | Boiling point | 459.3±47.0 °C(Predicted) | | density | 1.170±0.06 g/cm3(Predicted) | | pka | 11.85±0.10(Predicted) |
| | N,N-Dimethyl-4-(5-methyl-1H-benzo[d]imidazol-2-yl)benzenamine Usage And Synthesis |
| Uses | V-161 is the orally active inhibitor for Na+-V-ATPase with an IC50 of 144 nM. V-161 inhibits Enterococcus hirae and Vancomycin-resistant Enterococcus faecium (VRE) under alkaline condition with MIC of 4 μg/mL and 4 μg/mL. V-161 inhibits colonization of VRE in mouse small intestine[1]. | | References | [1] Suzuki K, et al., Na+-V-ATPase inhibitor curbs VRE growth and unveils Na+ pathway structure. Nat Struct Mol Biol. 2024 Nov 21. DOI:10.1038/s41594-024-01419-y |
| | N,N-Dimethyl-4-(5-methyl-1H-benzo[d]imidazol-2-yl)benzenamine Preparation Products And Raw materials |
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