2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid

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2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid manufacturers

  • ABT-472
  • ABT-472 pictures
  • $1980.00
  • 2026-05-11
  • CAS:943650-25-7
  • Purity:
  • Supply Ability: 10g
2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid Basic information
Product Name:2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid
Synonyms:CS-2220;2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid;A-620223 (HCl salt);2-(1-Propylpiperidin-4-yl)-1H-benzo[d]iMidazole-7-carboxaMide succinate;A-620223 (Succinate);ABT 472;Butanedioic acid compd. with 2-(1-propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamide;AKOS016845980
CAS:943650-25-7
MF:C20H28N4O5
MW:404.46012
EINECS:
Product Categories:
Mol File:943650-25-7.mol
2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid Structure
2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid Chemical Properties
storage temp. 2-8°C
Safety Information
MSDS Information
2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid Usage And Synthesis
UsesA-620223 succinate (ABT-472) is an orally available poly(ADP-ribose) polymerase (PARP) inhibitor. A-620223 succinate (ABT-472) exhibits very good potency against the PARP-1 enzyme with a Ki value of 8 nM and an EC50 value of 3 nM in whole cell assay, making it useful in cancer research[1].
References[1] Penning TD, et al. Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer. Bioorg Med Chem. 2008 Jul 15;16(14):6965-75. DOI:10.1016/j.bmc.2008.05.044
2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid Preparation Products And Raw materials
Tag:2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid(943650-25-7) Related Product Information
2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamidebutanedioicacid 2-(1-Propyl-4-piperidinyl)-1H-benzimidazole-7-carboxamide N-(piperidin-4-ylmethyl)-2-(propan-2-yl)-1H-1,3-benzodiazole-4-carboxamide