镰叶芹二醇
| 中文名称 | 镰叶芹二醇 |
|---|---|
| 中文同义词 | 镰叶芹二醇;发卡二醇;(3R,8S,Z)-十七碳-1,9-二烯-4,6-二炔-3,8-二醇;(+)-(3R,8S)-镰叶芹二醇;镰叶芹二醇,法卡林二醇,福尔卡烯炔二醇,(3R,3S|)-法卡林二醇;FALCARINDIOL|||镰叶芹二醇;化合物:(+)-(3R,8S)-Falcarindiol;化合物：(+)-(3R,8S)-Falcarindiol |
| 英文名称 | Falcarindiol |
| 英文同义词 | 1,9-Heptadecadiene-4,6-diyne-3,8-diol,(3R,8S,9Z)-;(3R,8S,9Z)-1,9-Heptadecadiene-4,6-diyne-3,8-diol;Falcarindiol/(3R),(8S)-Falcarindiol;8S)-Falcarindiol;(3R,8S,Z)-Heptadeca-1,9-dien-4,6-diyne-3,8-diol;(+)-(3R,8S)-Falcarindiol - [F88371];(+)-(3R,8S)-falcarindiol;(3R,8S)-Falcarindiol |
| CAS号 | 225110-25-8 |
| 分子式 | C17H24O2 |
| 分子量 | 260.37 |
| EINECS号 | |
| 相关类别 | 标准品-对照品;对照品;标准品;标准品 -中药标准品;Aliphatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol文件 | 225110-25-8.mol |
| 结构式 |  |
镰叶芹二醇 性质
| 沸点 | 408.2±45.0 °C(Predicted) |
|---|---|
| 密度 | 1.000±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。 |
| 形态 | 油状 |
| 酸度系数(pKa) | 11.65±0.20(Predicted) |
| 颜色 | Colorless to light yellow |
Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) 是一种天然的聚乙炔化合物，存在于伞形科的许多植物中。Falcarindiol 可抑制LPS刺激的 inducible nitric oxide synthase (iNOS)、tumor necrosis factor alpha (TNFα)、interleukin-6 (IL-6) 和 interleukin-1 beta (IL-1β) 的表达。Falcarindiol 可减弱LPS诱导的 JNK、ERK、STAT1 和 STAT3 信号分子的激活。Falnidamol 是一种具有抗癌活性的嘧啶嘧啶类化合物。
| Target | Value |
|
iNOS
() | |
|
TNFα
() | |
|
IL-6
() | |
|
IL-1β
() | |
|
JNK
() | |
|
|
用途
Falcarindiol was isolated as an algicidal principle against the harmful red tide dinoflagellate, Heterocapsa circularisquama, from Notopterygii Rhizoma through bioassay-guided separation.To determine
the ambiguous absolute structure of this active principle, all three stereoisomers as well as falcarindiol were synthesized. 聽As a result of intensive analytical of their physicochemical properties, t
he configuration of Falcarinfiol was revealed to be 3R,8S. 聽(3S,8S)- and (3S,8R)-isomers were found to exhibit more potent algicidal activity than (3R,8S)-Falcarindiol isolated from Notopterygii Rhizo
ma.用途
用于含量测定/鉴定/药理实验等。安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-N1976 | 镰叶芹二醇 (+)-(3R,8S)-Falcarindiol | 225110-25-8 | 1 mg | 500元 |
| 2026/06/05 | HY-N1976 | 镰叶芹二醇 (+)-(3R,8S)-Falcarindiol | 225110-25-8 | 5 mg | 1500元 |