5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one

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5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one manufacturers

5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one Basic information
Product Name:5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one
Synonyms:5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one;2H-Thieno(2,3-e)(1,4)diazepin-2-one, 1,3-dihydro-5-(o-chlorophenyl)-7-ethyl-;1,3-dihydro-5-(o-chlorophenyl)-7-ethyl-2H-Thieno(2,3-e)(1,4)diazepin-2-one;N-DesMethyl ClotiazepaM;5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno(2,3-e)(1,4)diazepin-2-one;5-(2-Chlorophenyl)-7-ethyl-1H-thieno[2,3-e][1,4]diazepin-2(3H)-one;2H-Thieno[2,3-e]-1,4-diazepin-2-one, 5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-;Desmethylclotiazepam
CAS:33671-37-3
MF:C15H13ClN2OS
MW:304.79
EINECS:
Product Categories:Agonist, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol File:33671-37-3.mol
5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one Structure
5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one Chemical Properties
Melting point 208-210°C (dec.)
Boiling point 479.9±45.0 °C(Predicted)
density 1.39
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka13.08±0.40(Predicted)
form Solid
color Off-White to Beige
Safety Information
MSDS Information
5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one Usage And Synthesis
DescriptionDesmethylclotiazepam (Item No. 27838) is an analytical reference standard categorized as a thienodiazepine. It is an active metabolite of clotiazepam. This product is intended for research and forensic applications.
Chemical PropertiesOff-white Solid
UsesClotiazepam (C587410) metabolite, with central nervous depressant and anxiolytic activity.
References[1] R ARENDT  D J G  H R Ochs. Electron capture GLC analysis of the thienodiazepine clotiazepam. Preliminary pharmacokinetic studies.[J]. Arzneimittel-Forschung-Drug Research, 1982, 32 4: 453-455.
[2] LEMAIRE‐HURTEL A, ALVAREZ J. Drugs Involved in Drug-Facilitated Crime—Pharmacological Aspects[C]. 1900: 0. DOI: 10.1016/b978-0-12-416748-3.00003-7
5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one Preparation Products And Raw materials
Preparation ProductsCLOTIAZEPAM-->Metizolam-->5-(o-Chlorophenyl)-7-ethyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepine-2-thione
Tag:5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one(33671-37-3) Related Product Information
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