SAHA-BPyne manufacturers
- SAHA-BPyne
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- $1650.00
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2026-05-11
- CAS:930772-88-6
- Purity:
- Supply Ability: 10g
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| | SAHA-BPyne Basic information |
| Product Name: | SAHA-BPyne | | Synonyms: | SAHA-BPyne;N-[4-[4-(hex-5-ynoylamino)benzoyl]phenyl]-N'-hydroxyoctanediamide;Octanediamide, N1-hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-;SAHA BPyne,SAHABPyne;N1-Hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-octanediamide;SAHA-BPyne(solution in methanol) | | CAS: | 930772-88-6 | | MF: | C27H31N3O5 | | MW: | 477.55 | | EINECS: | | | Product Categories: | | | Mol File: | 930772-88-6.mol |  |
| | SAHA-BPyne Chemical Properties |
| density | 1.237±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 5 mg/ml; Methanol: 5 mg/ml | | pka | 9.48±0.20(Predicted) |
| | SAHA-BPyne Usage And Synthesis |
| Uses | SAHA-BPyne is an activity-based protein profiling (ABPP) probe for detecting HDAC activity, which covalently labels the proximal proteins through a photoactivation. SAHA-BPyne inhibits HDAC activity in HeLa nuclear lysate with an IC50 of less than 5 μM[1]. | | References | [1] Salisbury CM, et al., Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes. J Am Chem Soc. 2008 Feb 20;130(7):2184-94. DOI:10.1021/ja074138u |
| | SAHA-BPyne Preparation Products And Raw materials |
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