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| | Methyl 4-chloro-3-oxo-butanoate Basic information |
| | Methyl 4-chloro-3-oxo-butanoate Chemical Properties |
| Melting point | 14-16 °C | | Boiling point | 85 °C/4 mmHg (lit.) | | density | 1.305 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.456(lit.) | | Fp | 217 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) | | form | Liquid | | pka | 9.54±0.46(Predicted) | | Specific Gravity | 1.28 | | color | Colorless | | Water Solubility | 71 g/L (20 ºC) | | BRN | 1759939 | | Stability: | Moisture Sensitive | | InChI | 1S/C5H7ClO3/c1-9-5(8)2-4(7)3-6/h2-3H2,1H3 | | InChIKey | HFLMYYLFSNEOOT-UHFFFAOYSA-N | | SMILES | COC(=O)CC(=O)CCl | | LogP | 1.010 (est) | | CAS DataBase Reference | 32807-28-6(CAS DataBase Reference) | | NIST Chemistry Reference | Butanoic acid, 4-chloro-3-oxo-, methyl ester(32807-28-6) | | EPA Substance Registry System | Methyl 4-chloroacetoacetate (32807-28-6) |
| Hazard Codes | T | | Risk Statements | 25-34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 2810 6.1/PG 2 | | WGK Germany | 3 | | RTECS | AK5115000 | | F | 19 | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29183000 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral |
| | Methyl 4-chloro-3-oxo-butanoate Usage And Synthesis |
| Chemical Properties | Methyl 4-chloro-3-oxo-butanoate is clear slightly yellow to yellow-orange liquid | | Uses | γ-Chloroacetic acid derivative with acute toxicity used in the preparation of insecticides. | | Uses | Reacts with symmetric allylic diacetates or dicarbonates in the presence of a palladium catalyst to give dihyrofurans. | | Application | Methyl 4-chloro-3-oxobutyrate is an important organic synthesis intermediate, primarily used as a precursor in the synthesis of various insecticides. Furthermore, it plays a crucial role in the pharmaceutical industry, serving as one of the starting materials for the preparation of drug intermediates such as atorvastatin. |
| | Methyl 4-chloro-3-oxo-butanoate Preparation Products And Raw materials |
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