- EGCG Octaacetate
-
- $80.00
-
2026-07-15
- CAS:148707-39-5
- Purity: 97.53%
- Supply Ability: 10g
|
| Product Name: | AcEGCG | | Synonyms: | AcEGCG;Peracetylated epigallocatechin-3-gallate;(-)-Epigallocatechin gallate octaacetate ester;Epigallocatechin gallate octaacetate;Benzoic acid, 3,4,5-tris(acetyloxy)-, (2R,3R)-5,7-bis(acetyloxy)-3,4-dihydro-2-[3,4,5-tris(acetyloxy)phenyl]-2H-1-benzopyran-3-yl ester;Inhibitor,EGCG Octaacetate,prodrug,gram-negative bacteria,Bacterial,inhibit,colitis-driven colon cancer,PI3K/Akt/NFκB phosphorylation,AcEGCG,p65 acetylation,gram-positive bacteria;5-((((2R,3R)-5,7-Diacetoxy-2-(3,4,5-triacetoxyphenyl)chroman-3-yl)oxy)carbonyl)benzene-1,2,3-triyl triacetate;EGCG Octaacetate, 10 mM in DMSO | | CAS: | 148707-39-5 | | MF: | C38H34O19 | | MW: | 794.67 | | EINECS: | | | Product Categories: | | | Mol File: | 148707-39-5.mol |  |
| | AcEGCG Chemical Properties |
| Melting point | 114.3-115.1 °C | | Boiling point | 879.7±65.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml,DMSO: 15 mg/ml | | form | Solid | | color | White to off-white |
| | AcEGCG Usage And Synthesis |
| Uses | EGCG Octaacetate (AcEGCG) is a proagent of Green tea epigallocatechin-3-gallate (EGCG). EGCG Octaacetate decreases the proinflammatory mediator levels by down-regulating of PI3K/Akt/NFκB phosphorylation and p65 acetylation. EGCG Octaacetate reduces colitis-driven colon cancer in mice. EGCG octaacetate is the potential antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB)[1][2][3]. | | References | [1] Wang CC, et al. Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice. Angiogenesis. 2013 Jan;16(1):59-69. DOI:10.1007/s10456-012-9299-4
[2] KalaiselviIgnasimuthu, et al. Enhanced bioaccessibility of green tea polyphenols and lipophilic activity of EGCG octaacetate on gram-negative bacteria. Volume 105, May 2019, Pages 103-109.
[3] Yi-Shiou Chiou, et al. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. J Agric Food Chem. 2012 Apr 4;60(13):3441-51. DOI:10.1021/jf300441p |
| | AcEGCG Preparation Products And Raw materials |
|