4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline

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4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline Basic information
Product Name:4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline
Synonyms:N-(1,3-BENZODIOXOL-5-YLMETHYL)-6-METHOXY-4-QUINAZOLINAMINE;N-(benzo[d][1,3]dioxol-5-ylmethyl)-6-methoxyquinazolin-4-amine;4-Quinazolinamine, N-(1,3-benzodioxol-5-ylmethyl)-6-methoxy-;4-{[3′,4′-(Methylenedioxy)benzyl]amino}-6-methoxyquinazoline, CAS 150450-42-3;4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline
CAS:150450-42-3
MF:C17H15N3O3
MW:309.32
EINECS:
Product Categories:
Mol File:150450-42-3.mol
4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline Structure
4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline Chemical Properties
Boiling point 504.4±45.0 °C(Predicted)
density 1.372±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 5mg/mL
pka5.53±0.50(Predicted)
form solid
color white
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline Usage And Synthesis
UsesPotent and specific inhibitor of cGMP-specific phosphodiesterase (PDE V, IC50 = 230 nM). Elevates the intracellular cGMP level without causing a change in the cAMP level in isolated porcine coronary arteries. Has no effect on other PDE isoenzymes.
DefinitionChEBI: N-(1,3-benzodioxol-5-ylmethyl)-6-methoxy-4-quinazolinamine is a member of quinazolines.
Biological ActivityPrimary Target
CGMP-PDEV
4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline Preparation Products And Raw materials
Tag:4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline(150450-42-3) Related Product Information
4-[[3',4'-(Methylenedioxy)benzyl]amino]-6-methoxyquinazoline 6-Methoxy-quinazolin-4-ylamine N-(1,3-BENZODIOXOL-5-YLMETHYL)-6,7-DIMETHOXY-4-QUINAZOLINAMINE 6-Quinazolinol (6CI,7CI,8CI,9CI) N-(1,3-BENZODIOXOL-5-YLMETHYL)-N-METHYLAMINE N-(1,3-BENZODIOXOL-5-YLMETHYL)-4-QUINAZOLINAMINE N-Benzylquinazoline-4-amine 4-((3,4-(methylenedioxy)benzyl)amino)-6,7,8-trimethoxyquinazoline (4-METHOXYBENZYL)(QUINAZOLIN-4-YL)AMINE