1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt

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1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt Basic information
Product Name:1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt
Synonyms:1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt;Azide MegaStokes dye 735;1-(3-azidopropyl)-4-[(E)-2-(6-diethylaminobenzofuran-2-yl)vinyl]-3-sulfonatopyridinium;Azide MegaStokes dye 735 for copper catalyzed click labeling
CAS:1246853-82-6
MF:C22H25N5O4S
MW:455.53
EINECS:
Product Categories:
Mol File:1246853-82-6.mol
1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt Structure
1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt Chemical Properties
storage temp. -20°C
form powder
InChI1S/C22H25N5O4S/c1-3-27(4-2)19-8-6-18-14-20(31-21(18)15-19)9-7-17-10-13-26(12-5-11-24-25-23)16-22(17)32(28,29)30/h6-10,13-16H,3-5,11-12H2,1-2H3
InChIKeyCGMCCNZFQJOMRA-UHFFFAOYSA-N
SMILESCCN(CC)c1ccc2cc(\C=C\c3cc[n+](CCCN=[N+]=[N-])cc3S([O-])(=O)=O)oc2c1
Safety Information
WGK Germany 3
Storage Class13 - Non Combustible Solids
MSDS Information
1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt Usage And Synthesis
UsesAzide MegaStokes dye 735 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
General DescriptionThe MegaStokes dyes for click" biological labeling, licensed by LuminoChem are virtually covering the whole visible spectrum reaching the infra-red regime. Besides dyes that are being capable of participating in classical copper catalyzed 1,3-dipolar cycloaddition reaction with the counterparting function, we also provide dyes containing cyclooctyne moiety an alkyne derivative that enables copper free clicking to azides.
These dyes are noteworthy for their large Stokes-shift (120 or 125 nm). Dyes for this kind are exceptionally useful in fluorescence resonance electron transfer (FRET) applications as they do not interfere with the spectral bands of the second fluorophore a common problem in FRET technology. Azido sugars have been used for click-labeling of surface glycoproteins, recently. We have adapted this system to demonstrate the ability of our dyes to undergo bioorthogonal labeling reaction, efficiently. Prior to labeling, Chinese hamster ovary (CHO) cells were incubated with these MegaStockesdyes to test the possible cytostatic effects of these dyes. Experimental results have shown that neither dye is toxic up to 50 μM concentration.
References[1] Sultana M, et al. A review on experimental chemically modified activated carbon to enhance dye and heavy metals adsorption[J]. Cleaner engineering and technology, 2022, 6: 100382.
1-(3-Azidopropyl)-4-{2-[6-(diethylamino)-2-benzofuranyl]ethenyl}-3-sulfo-pyridinium inner salt Preparation Products And Raw materials
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