SCARA3

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SCARA3 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
SCARA3 Basic information
Product Name:SCARA3
Synonyms:Anti-SCARA3 antibody produced in rabbit;APC7;CSR1;SCARA3;Anti-ANAPC7 antibody produced in rabbit;Anti-Anaphase promoting complex subunit 7;Monoclonal Anti-SCARA3 antibody produced in mouse;Anti-APC7
CAS:2234275-84-2
MF:C18H15N5O
MW:317.35
EINECS:
Product Categories:
Mol File:2234275-84-2.mol
SCARA3 Structure
SCARA3 Chemical Properties
Boiling point 575.269±60.00 °C(Press: 760.00 Torr)(predicted)
density 1.298±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. -20°C
pka4.858±0.10(predicted)
form buffered aqueous solution
biological sourcerabbit
Safety Information
WGK Germany WGK 1
Storage Class10 - Combustible liquids
MSDS Information
SCARA3 Usage And Synthesis
UsesAP-C7 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 5.0. AP-C7 only weakly inhibits cGKII-dependent anion secretion[1].
Biological ActivityScavenger receptor class A member 3 (SCARA3) protects cells against ultraviolet (UV) irradiation and oxidative stress. Reduced expression of SCARA3 increases oxidative stress in keratoconus (KC) cells in vitro. Quantitative polymerase chain reaction (PCR) analysis proves th at SCARA3 transcript is highly expressed in ovarian/primary peritoneal carcinoma (OC/PPC) compared to breast carcinoma effusions. SCARA3 represses tumor growth and metastasis of prostate cancer. Therefore, it can be used as a potential therapeutic target for treating aggressive types of prostate cancer.
References[1] Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181. DOI:10.1074/jbc.RA118.002835
SCARA3 Preparation Products And Raw materials
Tag:SCARA3(2234275-84-2) Related Product Information
SCARA3 DT-2 acetate APC1 beta-Phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate sodium salt Arg-Lys-Arg-Ala-Arg-Lys-Glu SMA4