- Propargyl-PEG2-COOtBu
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2026-07-24
- CAS:1807503-80-5
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG2-t-butyl ester Basic information |
| Product Name: | Propargyl-PEG2-t-butyl ester | | Synonyms: | Propargyl-PEG2-t-butyl ester;Alkyne-PEG2-CH2CH2COOtBu;PROPARGYL-PEG2-CH2CH2COOTBU;Propargyl-PEG2-COOtBu;Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 1,1-dimethylethyl ester;Propargyl-PEG2-Boc;Propargyl-PEG2-t-Bu Ester;Propargyl-PEG1-CH2CH2COOtBu/Propanoic acid, 3-[2-(2-propyn-1-yloxy)ethoxy]-, 1,1-dimethylethyl ester | | CAS: | 1807503-80-5 | | MF: | C12H20O4 | | MW: | 228.28 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1807503-80-5.mol |  |
| | Propargyl-PEG2-t-butyl ester Chemical Properties |
| Boiling point | 290.5±20.0 °C(Predicted) | | density | 1.007±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Colorless to light yellow |
| | Propargyl-PEG2-t-butyl ester Usage And Synthesis |
| Description | Propargyl-PEG2-t-butyl ester is a PEG linker that enables Click Chemistry reactions with azide-bearing compounds or biomolecules; copper will be required for catalyzation. Under acidic conditions, the t-butyl group can be removed. | | Uses | Propargyl-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Propargyl-PEG2-t-butyl ester Preparation Products And Raw materials |
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