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T&W GROUP |
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021-61551611 13296011611 |
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MPEG12-NH2 manufacturers
- m-PEG12-amine
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- $40.00
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2026-07-15
- CAS:1977493-48-3
- Purity: 99.92%
- Supply Ability: 10g
- mPEG12-NH2
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-
2026-01-28
- CAS:1977493-48-3
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 300kg
- m-PEG12-amine
-
-
2025-06-07
- CAS:1977493-48-3
- Min. Order: 5g
- Purity: >95.00%
- Supply Ability: 5g
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| | MPEG12-NH2 Basic information |
| Product Name: | MPEG12-NH2 | | Synonyms: | m-PEG13-amine;3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine;mPEG12-NH2/3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine;m-PEG12-amine ，S0603 | | CAS: | 1977493-48-3 | | MF: | C25H53NO12 | | MW: | 559.69 | | EINECS: | | | Product Categories: | | | Mol File: | 1977493-48-3.mol |  |
| | MPEG12-NH2 Chemical Properties |
| Boiling point | 583.6±45.0 °C(Predicted) | | density | 1.073±0.06 g/cm3(Predicted) | | storage temp. | -20°C, protect from light, stored under nitrogen | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 8.74±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow | | InChI | InChI=1S/C25H53NO12/c1-27-4-5-29-8-9-31-12-13-33-16-17-35-20-21-37-24-25-38-23-22-36-19-18-34-15-14-32-11-10-30-7-6-28-3-2-26/h2-26H2,1H3 | | InChIKey | MSKSQCLPULZWNO-UHFFFAOYSA-N | | SMILES | C(N)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
| | MPEG12-NH2 Usage And Synthesis |
| Description | m-PEG12-amine is a monodisperse PEG linker containing an amino group, It is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. | | IC 50 | PEGs; Non-cleavable Linker | | References | [1] Vasco AV, et al. A Multicomponent Stapling Approach to Exocyclic Functionalized Helical Peptides: Adding Lipids, Sugars, PEGs, Labels, and Handles to the Lactam Bridge. Bioconjug Chem. 2019 Jan 16;30(1):253-259. DOI:10.1021/acs.bioconjchem.8b00906
[2] Joseph Fox, et al. Methods for inducing bioorthogonal reactivity. WO2017106427A1. |
| | MPEG12-NH2 Preparation Products And Raw materials |
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