| Company Name: |
parabiochem |
| Tel: |
025-83453382-8005 |
| Email: |
sale@parabiochem.com |
Evenamide manufacturers
- Evenamide
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- $35.00
-
2026-07-17
- CAS:1092977-61-1
- Purity: 96.74%
- Supply Ability: 10g
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| | Evenamide Basic information |
| Product Name: | Evenamide | | Synonyms: | Evenamide;2-((3-butoxyphenethyl)amino)-N,N-dimethylacetamide;N2-[2-(3-Butoxyphenyl)ethyl]-N,N-dimethylglycinamide;NW-3509;Acetamide, 2-[[2-(3-butoxyphenyl)ethyl]amino]-N,N-dimethyl-;psychosis,mania,voltage,Inhibitor,inhibit,gated,Na+ channels,Na channels,aggressiveness,schizophrenia,NW3509,channel,sodium,Sodium Channel,VGSC,depression,NW 3509,Evenamide;Evenamide, 10 mM in DMSO | | CAS: | 1092977-61-1 | | MF: | C16H26N2O2 | | MW: | 278.39 | | EINECS: | | | Product Categories: | | | Mol File: | 1092977-61-1.mol |  |
| | Evenamide Chemical Properties |
| Boiling point | 412.1±30.0 °C(Predicted) | | density | 1.012±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 290 mg/mL (1041.70 mM) | | form | Liquid | | pka | 7.99±0.19(Predicted) | | color | Colorless to light yellow |
| | Evenamide Usage And Synthesis |
| Uses | Evenamide (NW-3509) is an orally available voltage-gated sodium channel (VGSC) blocker (Ki=0.4 μM) for the research of schizophrenia. Evenamide shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness[1][2]. | | in vivo | Evenamide is active in a wide range of psychiatric animal models in monotherapy and addon to antipsychotics. Evenamide is effective in attenuating the social interaction deficit in Cl 395 (PCP)-impaired rats (MED=1 mg/kg po)[2]. | | References | [1] Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.
[2] Faravelli, et al. P.3.f.022 Evenamide (formerly NW-3509) targets new mechanisms, and represents a new approach to the management of untreated symptoms in schizophrenia. |
| | Evenamide Preparation Products And Raw materials |
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