- TRC051384 HCl
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- $64.00 / 5mg
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2026-04-13
- CAS:1333327-56-2
- Min. Order:
- Purity: 98.29%
- Supply Ability: 10g
- TRC051384
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- $1.00 / 1g
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2019-12-24
- CAS:1333327-56-2
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 20kg
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| | TRC051384 Basic information |
| Product Name: | TRC051384 | | Synonyms: | TRC051384 HCl;TRC051384 Hydrochloride;TRC051384 HydrochL;1-(2-Morpholinoethyl)-3-(4-(3-(6-morpholinopyridin-2-yl)acryloyl)phenyl)urea hydrochloride;TRC051384 HCl, 10 mM in DMSO | | CAS: | 1333327-56-2 | | MF: | C25H32ClN5O4 | | MW: | 502.01 | | EINECS: | | | Product Categories: | API | | Mol File: | 1333327-56-2.mol |  |
| | TRC051384 Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| | TRC051384 Usage And Synthesis |
| Uses | TRC051384 hydrochloride is a potent inducer of heat shock protein 70 (HSP70). TRC051384 hydrochloride exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 hydrochloride can be used for the research of ischemic stroke[1][2]. | | References | [1] Mohanan A, et, al. Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer. Neuropharmacology. 2011 May;60(6):991-9. DOI:10.1016/j.neuropharm.2010.12.003
[2] Chen T, et, al. HSP70 attenuates neuronal necroptosis through the HSP90α-RIPK3 pathway following neuronal trauma. Mol Biol Rep. 2023 Sep;50(9):7237-7244. DOI:10.1007/s11033-023-08619-7 |
| | TRC051384 Preparation Products And Raw materials |
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