N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-Boc
CAS:2112731-94-7
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-Boc
CAS:2112731-94-7
Package:2mg;39USD
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester
CAS:2112731-94-7
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester
CAS:2112731-94-7
Purity:>95.00% Package:500mg
Company Name: Aladdin Scientific
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Products Intro: Product Name:N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester
CAS:2112731-94-7
Purity:98% Package:$1051.9/100mg;$2041.9/250mg;$3301.9/500mg;Bulk package Remarks:98%

N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester manufacturers

N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester Basic information
Product Name:N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester
Synonyms:N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester;N-(Azido-PEG3)-N-Boc-PEG4-Boc
CAS:2112731-94-7
MF:C28H54N4O11
MW:622.74856
EINECS:
Product Categories:
Mol File:2112731-94-7.mol
N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester Structure
N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester Chemical Properties
storage temp. Storage temp. 2-8°C
form Viscous Liquid
color Colorless to light yellow
Safety Information
MSDS Information
N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester Usage And Synthesis
DescriptionN-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester is a branched molecule with a terminal azide group and a t-butyl ester group. Azide (N3) enables PEGylation via Click Chemistry. Boc group and the t-butyl protected carboxyl group can be deprotected under mild acidic conditions.
UsesN-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50PEGs; Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Azido-PEG3)-N-Boc-PEG4-t-butyl ester Preparation Products And Raw materials
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