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| | 3-(4-Bromophenyl)propionitrile Basic information | | Uses |
| Product Name: | 3-(4-Bromophenyl)propionitrile | | Synonyms: | 3-(4-Bromophenyl)propionitrile 98%;3-(4-Bromophenyl)propanenitrile 98%;Benzenepropanenitrile, 4-broMo-;3-(4-Bromophenyl)propionitrile, 2-(4-Bromophenyl)ethyl cyanide;3-(4-Bromophenyl)propanenitrile98%;4-Bromobenzenepropanenitrile;3-(4-bromophenyl)propylnitrile;3-(4-Bromophenyl)propanenitrile | | CAS: | 57775-08-3 | | MF: | C9H8BrN | | MW: | 210.07 | | EINECS: | | | Product Categories: | | | Mol File: | 57775-08-3.mol |  |
| | 3-(4-Bromophenyl)propionitrile Chemical Properties |
| Boiling point | 118°C 1mm | | density | 1,42 g/cm3 | | storage temp. | Sealed in dry,Room Temperature | | Specific Gravity | 1.42 | | Appearance | White to off-white Solid | | CAS DataBase Reference | 57775-08-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 20/21/22-36/37/38-52 | | Safety Statements | 26-36/37/39 | | RIDADR | 3276 | | Hazard Note | Irritant | | HazardClass | IRRITANT, IRRITANT-HARMFUL | | HS Code | 2926907090 |
| | 3-(4-Bromophenyl)propionitrile Usage And Synthesis |
| Uses | 3-(4-bromophenyl)propionitrile is a nitrile compound that can be used as an intermediate in organic synthesis to prepare other heterocyclic compounds. | | Synthesis | General procedure for the synthesis of 3-(4-bromophenyl)propanenitrile from diethyl cyanomethylphosphonate and p-bromobenzaldehyde: (2) Prop-2-enenenitrile E/Z mixture of 3-(4-bromophenyl)pyridine (34.8 g, 0.63 L) was dissolved in methanol (0.21 L), and sodium borohydride (8.2 g) was slowly added at 0 °C under nitrogen protection. The reaction mixture was stirred at 100 °C for 1 hour. After completion of the reaction, the reaction solution was concentrated, water was added and the mixture was extracted with ethyl acetate. The organic layer was washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate, filtered and the solvent was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (eluent ratio: hexane:ethyl acetate=100:0→65:35) to give the yellow oily product 3-(4-bromophenyl)propionitrile (28.1 g). | | References | [1] Patent: JP2015/231988, 2015, A. Location in patent: Paragraph 0328; 0329 |
| | 3-(4-Bromophenyl)propionitrile Preparation Products And Raw materials |
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