| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
MST-312 manufacturers
- MST-312
-
- $44.00
-
2026-04-22
- CAS:368449-04-1
- Purity: 99.61%
- Supply Ability: 10g
|
| | MST-312 Basic information |
| Product Name: | MST-312 | | Synonyms: | Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem;TELOMERASE INHIBITOR IX;MST-312;N,N'-BIS(2,3-DIHYDROXYBENZOYL)-1,3-PHENYLENEDIAMINE;N,N′-1,3-Phenylenebis-[2,3-dihydroxy-benzamide];N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide;Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-;MST-312 >=98% (HPLC) | | CAS: | 368449-04-1 | | MF: | C20H16N2O6 | | MW: | 380.35 | | EINECS: | | | Product Categories: | | | Mol File: | 368449-04-1.mol |  |
| | MST-312 Chemical Properties |
| Boiling point | 526.7±50.0 °C(Predicted) | | density | 1.578±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: ≥20mg/mL | | form | White solid | | pka | 7.70±0.35(Predicted) | | color | off-white to light tan | | InChI | 1S/C20H16N2O6/c23-15-8-2-6-13(17(15)25)19(27)21-11-4-1-5-12(10-11)22-20(28)14-7-3-9-16(24)18(14)26/h1-10,23-26H,(H,21,27)(H,22,28) | | InChIKey | MIQUEZGHEJGPJB-UHFFFAOYSA-N | | SMILES | Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O |
| Hazard Codes | N | | Risk Statements | 50 | | Safety Statements | 61 | | WGK Germany | 2 | | Storage Class | 11 - Combustible Solids |
| | MST-312 Usage And Synthesis |
| Uses | MST-312 has been used in cell invasion assay using mouse fibroblast cells (NIH-3T3) and in the co-immunoprecipitation experiments in colon fibroblast. | | Definition | ChEBI: N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide is a member of benzamides. | | General Description | A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 μM). | | Biochem/physiol Actions | Cell permeable: yes |
| | MST-312 Preparation Products And Raw materials |
|