- 1588-A4
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- $53.00
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2026-05-11
- CAS:1698027-20-1
- Purity: 98.59%
- Supply Ability: 10g
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| | tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Basic information |
| | tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Chemical Properties |
| Boiling point | 534.9±50.0 °C(Predicted) | | density | 1.521±0.06 g/cm3(Predicted) | | solubility | DMSO: Slightly soluble: 0.1-1 mg/ml | | pka | 10.06±0.70(Predicted) |
| | tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Usage And Synthesis |
| Description | 1588-A4 is a synthetic intermediate that has been used in the synthesis of the K-RasG12C inhibitor ARS1620 (Item No. 27915).1 WARNING This product is not for human or veterinary use. | | References | [1] MATTHEW R JANES. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.[J]. Cell, 2018, 172 3: 578-589.e17. DOI: 10.1016/j.cell.2018.01.006 |
| | tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Preparation Products And Raw materials |
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