tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate

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tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate manufacturers

  • 1588-A4
  • 1588-A4 pictures
  • $32.00
  • 2026-08-08
  • CAS:1698027-20-1
  • Purity: 98.59%
  • Supply Ability: 10g
tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Basic information
Product Name:tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate
Synonyms:1588-A4;tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate;1-Piperazinecarboxylic acid, 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-, 1,1-dimethylethyl ester;ARS-1620 Intermediate;1588-A-4,1588A4,1588 A4
CAS:1698027-20-1
MF:C17H19BrClFN4O2
MW:445.71
EINECS:
Product Categories:
Mol File:1698027-20-1.mol
tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Structure
tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Chemical Properties
Boiling point 534.9±50.0 °C(Predicted)
density 1.521±0.06 g/cm3(Predicted)
solubility DMSO: Slightly soluble: 0.1-1 mg/ml
pka10.06±0.70(Predicted)
Safety Information
MSDS Information
tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Usage And Synthesis
Description1588-A4 is a synthetic intermediate that has been used in the synthesis of the K-RasG12C inhibitor ARS1620 (Item No. 27915).1 WARNING This product is not for human or veterinary use.
References[1] MATTHEW R JANES. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.[J]. Cell, 2018, 172 3: 578-589.e17. DOI: 10.1016/j.cell.2018.01.006
tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Preparation Products And Raw materials
Tag:tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate(1698027-20-1) Related Product Information
2-Quinazolinecarboxylic acid, 7-bromo-6-chloro-4-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]-8-fluoro- Methylmagnesium iodide 3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid, 3-(7-bromo-2-chloro-6,8-difluoro-4-quinazolinyl)-, 1,1-dimethylethyl ester tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate 1-Piperazinecarboxylic acid, 4-(7-bromo-2,6-dichloro-8-fluoro-4-quinazolinyl)-3-methyl-, 1,1-dimethylethyl ester, (3R)-