N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine

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N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine manufacturers

  • CIA-1 Free base
  • CIA-1 Free base pictures
  • $31.00
  • 2026-08-14
  • CAS:452087-38-6
  • Purity: 99.00%
  • Supply Ability: 10g
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine Basic information
Product Name:N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine
Synonyms:N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine;CIA1;Thieno[2,3-d]pyrimidin-4-amine, N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-;CIA-1 (Free base);CIA-1(Free base）;N-(3,4-dimethoxyphenethyl)-6-methylthieno[2,3-d]pyrimidin-4-amine;18:0 mPEG2000 PE sodium
CAS:452087-38-6
MF:C17H19N3O2S
MW:329.42
EINECS:
Product Categories:
Mol File:452087-38-6.mol
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine Structure
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine Chemical Properties
Boiling point 529.6±50.0 °C(Predicted)
density 1.264±0.06 g/cm3(Predicted)
pka5.40±0.40(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine Usage And Synthesis
UsesNR2F2-IN-1 (free base) is a potent and selective orphan nuclear receptor COUP-TFII (NR2F2) inhibitor. NR2F2-IN-1 (free base) substantially inhibits COUP-TFII–driven NGFIA reporter expression. NR2F2-IN-1 (free base) directly binds to the COUP-TFII ligand-binding domain and disrupts COUP-TFII interaction with transcription regulators, including FOXA1, thus repressing COUP-TFII activity on target gene regulation[1].
References[1] Leiming Wang, et al. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment. Sci Adv. 2020 Apr 29;6(18):eaaz8031. DOI:10.1126/sciadv.aaz8031
N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine Preparation Products And Raw materials
Tag:N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine(452087-38-6) Related Product Information
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