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| | C16 3'-sulfo Galactosylceramide (d18:1/16:0) Basic information |
| Product Name: | C16 3'-sulfo Galactosylceramide (d18:1/16:0) | | Synonyms: | C16 3'-sulfo Galactosylceramide (d18:1/16:0);-sulfo Galactosylceramide (d18:1/16:0);C16 3’Hexadecanamide, N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-D-galactopyranosyl)oxy]methyl]-3-heptadecen-1-yl]-;N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-D-galactopyranosyl)oxy]methyl]-3-heptadecen-1-yl]-hexadecanamide;N-Hexadecanoylsulfatide, C16:0 CNS sulfolipid analog;C16 3′,-sulfo Galactosylceramide (d18:1/16:0) | | CAS: | 89771-78-8 | | MF: | C40H77NO11S | | MW: | 780.10448 | | EINECS: | | | Product Categories: | | | Mol File: | 89771-78-8.mol |  |
| | C16 3'-sulfo Galactosylceramide (d18:1/16:0) Chemical Properties |
| density | 1.13±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Chloroform:Methanol (2:1): Soluble | | form | A solid | | pka | -3.61±0.18(Predicted) |
| | C16 3'-sulfo Galactosylceramide (d18:1/16:0) Usage And Synthesis |
| Description | C16 3’-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. It is one of the most abundant sulfatides found in porcine brain and plasma. Levels of short-chain sulfatides, including C16-C20 3’-sulfo galactosylceramides, decrease throughout development in mice. C16 3’-sulfo Galactosylceramide inhibits retinal ganglion cell neurite outgrowth in vitro. It is increased in dried urine spots and dried blood spots from patients with metachromatic leukodystrophy (MLD). C16 3’-sulfo Galactosylceramide has been used as an internal standard for the quantification of sulfatides in rat cerebellum and isolated white matter from patients with multiple sclerosis. [Matreya, LLC. Catalog No. 1875] | | Uses | Palmitoyl sulfatide is an ester product. | | Definition | ChEBI: 1-(3-O-sulfo-beta-D-galactosyl)-N-palmitoylsphingosine is a D-galactosyl-N-acylsphingosine having a sulfo group at the 3-position on the galactose ring and palmitoyl as the N-acyl group. It is a N-acyl-beta-D-galactosylsphingosine and a galactosylceramide sulfate. | | References | [1] JENNIFER T. SAVILLE . Quantification of plasma sulfatides by mass spectrometry: Utility for metachromatic leukodystrophy[J]. Analytica Chimica Acta, 2017, 955: Pages 79-85. DOI: 10.1016/j.aca.2016.12.002
[2] GIORGIS ISAAC. Sulfatide with short fatty acid dominates in astrocytes and neurons[J]. The FEBS journal, 2006, 273 8: 1782-1790. DOI: 10.1111/j.1742-4658.2006.05195.x
[3] ALISSA M WINZELER. The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth.[J]. Journal of Neuroscience, 2011: 6481-6492. DOI: 10.1523/jneurosci.3004-10.2011
[4] MARIANA BARCENAS . Quantification of sulfatides in dried blood and urine spots from metachromatic leukodystrophy patients by liquid chromatography/electrospray tandem mass spectrometry[J]. Clinica Chimica Acta, 2014, 433: Pages 39-43. DOI: 10.1016/j.cca.2013.12.016
[5] BETH NOELLE MARBOIS . Analysis of sulfatide from rat cerebellum and multiple sclerosis white matter by negative ion electrospray mass spectrometry[J]. Biochimica et biophysica acta. Molecular and cell biology of lipids, 2000, 1484 1: Pages 59-70. DOI: 10.1016/s1388-1981(99)00201-2 |
| | C16 3'-sulfo Galactosylceramide (d18:1/16:0) Preparation Products And Raw materials |
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