Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt)

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Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt) Basic information
Product Name:Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt)
Synonyms:Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt)
CAS:
MF:C63H88N16O14S
MW:1325.53662
EINECS:
Product Categories:
Mol File:Mol File
Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt) Structure
Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt) Chemical Properties
solubility Formic Acid: 1 mg/ml
Safety Information
MSDS Information
Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt) Usage And Synthesis
DescriptionDabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-2, MMP-3, and MMP-9.1 Upon enzymatic cleavage by MMP-1, MMP-2, MMP-3, or MMP-9 at the Gly-Leu site, EDANS is separated from the Dabcyl quencher and its fluorescence can be used to quantify MMP-1, MMP-2, MMP-3, and MMP-9 activity.1,2 EDANS displays excitation/emission maxima of 340/485 nm, respectively.WARNING This product is not for human or veterinary use.
References[1] BOB BEEKMAN . Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological media[J]. FEBS Letters, 1996, 390 2: Pages 221-225. DOI: 10.1016/0014-5793(96)00665-5
[2] FRANSISKA S. H. KRISMASTUTI  Nicolas H V  Stephanie Pace. Porous Silicon Resonant Microcavity Biosensor for Matrix Metalloproteinase Detection[J]. Advanced Functional Materials, 2014, 24 23: 3639-3650. DOI: 10.1002/adfm.201304053
Dabcyl-GABA-PQGL-Glu(EDANS)-AK-NH2 (trifluoroacetate salt) Preparation Products And Raw materials
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