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| | Unguisin A Basic information |
| Product Name: | Unguisin A | | Synonyms: | Unguisin A;Cyclo(D-alanyl-D-tryptophyl-4-aminobutanoyl-D-alanyl-D-valyl-L-phenylalanyl-D-valyl) | | CAS: | 226956-06-5 | | MF: | C40H54N8O7 | | MW: | 758.90616 | | EINECS: | | | Product Categories: | | | Mol File: | 226956-06-5.mol |  |
| | Unguisin A Chemical Properties |
| Melting point | 105-115 °C | | Boiling point | 1202.9±65.0 °C(Predicted) | | density | 1.134±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | A solid | | pka | 13.22±0.70(Predicted) | | Sequence | Cyclo(Ala-Trp-{Oaa}-Ala-Val-Leu-Val) |
| | Unguisin A Usage And Synthesis |
| Description | Unguisin A is a cyclic heptapeptide originally isolated from the marine fungus E. unguis whose structure is comprised of amino acids and GABA.1 It binds to phosphate, pyrophosphate, and chloride but has no effect on chloride transport in a liposome-based assay.2 It exhibited moderate antibacterial activity against S. aureus and V. parahaemolyticus in one assay but no activity against a variety of bacteria, including S. aureus, in another.1,2 | | Uses | Unguisin A s a cyclic peptides that can be isolated from the marine-derived fungus Emericella unguis[1]. | | References | 1. Malmstrom, J. Unguisins A and B: New cyclic peptides from the marine-derived fungus Emericella unguis J. Nat. Prod. 62(5),787-789(1999).
2. Ariawan, A.D., Webb, J.E.A., Howe, E.N.W., et al. Cyclic peptide unguisin A is an anion receptor with high affinity for phosphate and pyrophosphate Org. Biomol. Chem. 15(14),2962-2967(2017). |
| | Unguisin A Preparation Products And Raw materials |
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