LEROCICLIB HCL ; G1T38 DIHYDROCHLORIDE ; G1T 38 DIHYDROCHLORIDE
| 中文名称 | LEROCICLIB HCL ; G1T38 DIHYDROCHLORIDE ; G1T 38 DIHYDROCHLORIDE |
|---|---|
| 中文同义词 | LEROCICLIB HCL ; G1T38 DIHYDROCHLORIDE ; G1T 38 DIHYDROCHLORIDE;化合物LEROCICLIB DIHYDROCHLORIDE;2'-((5-(4-异丙基哌嗪-1-基)吡啶-2-基)氨基)-7',8'-二氢-6'H-螺[环己烷-1,9'-吡嗪[1' ,2':1,5]吡咯并[2,3-D]嘧啶]-6'-酮双盐酸盐;来罗西利二盐酸盐 |
| 英文名称 | G1T38 dihydrochloride |
| 英文同义词 | G1T38 dihydrochloride;LEROCICLIB DIHYDROCHLORIDE (G1T38 DIHYDROCHLORIDE);Lerociclib dihydrochloride;5-(4-fluoroindolin-5-yl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride;Inhibitor,G1T38,Lerociclib,Lerociclib dihydrochloride,inhibit,CDK,Cyclin dependent kinase;2'-((5-(4-Isopropylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one;Lerociclib HCl |
| CAS号 | 2097938-59-3 |
| 分子式 | C26H35ClN8O |
| 分子量 | 511.07 |
| EINECS号 | |
| 相关类别 | 抑制剂 |
| Mol文件 | 2097938-59-3.mol |
| 结构式 |  |
LEROCICLIB HCL ; G1T38 DIHYDROCHLORIDE ; G1T 38 DIHYDROCHLORIDE 性质
| 储存条件 | Store at -20°C |
|---|---|
| 形态 | 固体 |
| 颜色 | 浅黄至黄色 |
| 水溶解性 | Water : 4 mg/mL (7.31 mM) |
Lerociclib dihydrochloride (G1T38 dihydrochloride) 是一种有效的选择性 CDK4/CDK6 抑制剂，抑制 CDK4/CyclinD1 和 CDK6/CyclinD3，IC50 值分别为 1 nM 和 2 nM。
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-112272A | LEROCICLIB HCL ; G1T38 DIHYDROCHLORIDE ; G1T 38 DIHYDROCHLORIDE Lerociclib dihydrochloride | 2097938-59-3 | 5mg | 1200元 |
| 2026/06/05 | HY-112272A | LEROCICLIB HCL ; G1T38 DIHYDROCHLORIDE ; G1T 38 DIHYDROCHLORIDE Lerociclib dihydrochloride | 2097938-59-3 | 10mg | 1950元 |