| Company Name: |
ChemOrigin Pharm |
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15026428026 19002516454 |
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ChemOrigin@126.com |
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| | RIPK2 inhibitor 1 Basic information |
| Product Name: | RIPK2 inhibitor 1 | | Synonyms: | RIPK2 inhibitor 1;Benzamide, 3-(benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]-;RIPK2-IN-3;3-Benzamido-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide;RIPK2 inhibitor | | CAS: | 1290490-78-6 | | MF: | C25H22N4O2 | | MW: | 410.47 | | EINECS: | | | Product Categories: | | | Mol File: | 1290490-78-6.mol |  |
| | RIPK2 inhibitor 1 Chemical Properties |
| storage temp. | 2-8°C | | solubility | Soluble to 100 mM in DMSO | | form | powder | | color | white to very dark gray | | InChI | 1S/C25H22N4O2/c1-17-11-12-20(16-22(17)28-24(30)18-7-4-3-5-8-18)25(31)27-21-10-6-9-19(15-21)23-26-13-14-29(23)2/h3-16H,1-2H3,(H,27,31)(H,28,30) | | InChIKey | OIIYBZHRYXJCHR-UHFFFAOYSA-N | | SMILES | CC1=CC=C(C(NC2=CC(C3=NC=CN3C)=CC=C2)=O)C=C1NC(C4=CC=CC=C4)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | RIPK2 inhibitor 1 Usage And Synthesis |
| Uses | RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor. RIPK2-IN-3 inhibits recombinant truncated RIPK2 with an IC50 of 6.39 μM. RIPK2-IN-3 can be used for research of inflammation and cancer[1]. | | Biological Activity | RIPK2 inhibitor 1 is a potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) th at potently inhibit NFKB activity and the proliferation of cancer cell lines. RIPK2 inhibitor 1 inhibits intestinal and lung inflammation in rodent models. | | storage | Store at -20°C | | References | [1] Shairaz BAKSH, et al. Ripk2 inhibitors. WO2019161495. |
| | RIPK2 inhibitor 1 Preparation Products And Raw materials |
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